« All Photo Galleries ‘Grey’s Anatomy’ Top 10 Couples

3. Arizona and Callie

Callie (Sara Ramirez) and Arizona (Jessica Capshaw) were gloriously goofy and in love, once upon a time. Not only was their relationship a groundbreaking one for television, it was also one that, at one point or another, viewers couldn’t help but root for.

Grey's Anatomy/ABC

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