« All Photo Galleries ‘Grey’s Anatomy’ Top 10 Couples

4. Owen and Cristina

Owen (Kevin McKidd) was Cristina’s (Sandra Oh) traditional happy ever after, even with his PTSD issues and disturbing habit of trying to strangle her in her sleep. Owen was the only man willing to be with Cristina and give her space to nurture her career ambitions at the same time. But, in the end, Owen wanted more than Cristina was willing to give and she left to follow her dreams.

Grey's Anatomy/ABC

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