6. April and Jackson
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6. April and Jackson

Jackson (Jesse Williams) and April (Sarah Drew) may be past the point of no return (#RIPJapril), but their relationship has provided some of the best and most heartbreaking storylines over the past few seasons, and for that, they deserve a top spot. But, let’s go back to the not-so romantic, but oh so sexy beginning: when April broke her vow to remain a virgin until marriage by having sex with Jackson. The relationship was delightfully forbidden, and for once, it wasn’t because he was her boss. April and Jackson’s relationship was unique for Grey’s, and their most recent storyline, involving the death of their child, was one of the most sob-worthy batch of episodes ever.

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