Oprah Winfrey, 55, known for a quarter century as the queen of talk shows, will end The Oprah Winfrey Show in 2011, it was announced Thursday night. The last show will air Sept. 9, 2011. Oprah is launching her own cable channel – OWN: The Oprah Winfrey Network – with the Discovery Channel and may decide to launch a version of the show on that network once it is up and running. (Photo: WENN)