Accomplished actress Julia Louis-Dreyfus, 57, has starred in many comedies and won many awards for her talents. Her collection of awards is about to grow too, as she will be honored with a Mark Twain Prize for American Humor later this year.

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On October 21, Louis-Dreyfus will be honored with her Mark Twain award, which only the world’s most acclaimed humorists receive, at the Kennedy Center. In addition to this award, Louis-Dreyfus won her sixth consecutive Emmy award for her performance as Selina Meyer on Veep.

Louis-Dreyfus has a celebrated history in comedy. She joined the cast of Saturday Night Live when she was 21, meeting Larry David on her final year. Afterwards, she starred in films — the most notable likely being 1989’s National Lampoon’s Christmas Vacation, where she worked with fellow SNL alumni Chevy Chase — before appearing as Elaine Benes on the iconic sitcom Seinfeld, which ran from 1990 to 1998.

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Following Seinfeld‘s finale, Louis-Dreyfus continued to pursue her craft, appearing as the lead in The New Adventures of Old Christine (2006 to 2010) and Veep, which began in 2011 and is still running. Moreover, she’s appeared on other programs as well, including in David’s Curb Your Enthusiasm.