Harry Potter and the Half-Blood Prince, the sixth installment of the hit series, has taken in $159.7 million at the box office since debuting last Wednesday. Potter, starring Daniel Radcliffe (pictured) and Alan Rickman (see Uinterview video, right), easily knocked off last week's winner Bruno. (Photo: WENN)

1. Harry Potter, $79.5 million

2. Ice Age, $17.7 million

3. Transformers, $13.8 million

4. Bruno, $8.4 million

5. The Hangover, $8.32 million

6. The Proposal, $8.3 million

7. Public Enemies, $7.6 million

8. Up, $3.1 million

9. My Sister's Keeper, $2.8 million

10. I Love You, Beth Cooper, $2.7 million