CANNES, FRANCE - MAY 18: Jesse Plemons attends the "Kinds Of Kindness" Photocall at the 77th annual Cannes Film Festival at Palais des Festivals on May 18, 2024 in Cannes, France. (Photo by Lionel Hahn/Getty Images)
Acclaimed actor Jesse Plemons addressed the speculation surrounding his recent physical transformation, revealing that, contrary to the rumors, his weight loss journey was the result of a deliberate lifestyle change rather than the use of the popular diabetes medication Ozempic.
Plemons, 36, explained that his decision to prioritize his health was motivated by his age and the demands of his role in the drama Civil War. The actor acknowledged the unfortunate timing of his fitness journey, as the widespread use of Ozempic for its “off-label” weight loss effects had coincided with his own transformation.
“It’s really unfortunate that I decided to get healthy when everyone decided to take Ozempic,” Plemons told the Los Angeles Times. “It doesn’t matter, everyone’s going to think I took Ozempic anyways.”
Plemons credited intermittent fasting as a critical factor in his successful health regimen and shared that several individuals had recommended the practice, which involves consuming all food within an eight-hour window. He said he was “surprised at how quickly it was effective.”
“So I lost a little bit before I did that part, and then I felt like I was in the rhythm. I was feeling better, and something shifted in my head. I just sort of got a handle on it,” the actor explained.
While Plemons has since dispelled the Ozempic rumors, several other celebrities have openly admitted they used prescription weight loss medications to achieve their fitness goals. In December 2023, Oprah Winfrey acknowledged using a medically approved weight loss drug and praised it for enabling her to live a healthier lifestyle.
In addition to Ozempic, the FDA-approved medications Wegovy and Mounjaro have also gained popularity due to their side effects on weight loss. Wegovy is a semaglutide injection specifically approved for the treatment of obesity and weight loss, while Mounjaro is the first diabetes drug to target a second hormone, GIP.
The FDA has warned about the possibility of severe side effects, such as thyroid C-cell tumors, pancreatitis, gallbladder problems, acute kidney injury, increased heart rate and suicidal behavior or thinking.
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