Chelsea Handler gathered together her best friends in show business for her last Chelsea Lately show. Among the big names to bid Handler goodbye, was Ellen DeGeneres, who confronted the nude host in the shower.

Chelsea Handler's Last 'Chelsea Lately' Show

On Tuesday night, Handler signed off late-night and said goodbye to E! after seven years with the help of her A-list pals, which included best friend Jennifer Aniston and her husband Justin Theroux, Courteney Cox, Sandra Bullock, Gwen Stefani, Melissa McCarthy, 50 Cent, Miley Cyrus, Vanessa Hudgens, Gerard Butler and more.

At the conclusion of the special, Handler recruited her pals to sing a song with lyrics set to "We Are the World." Stefani kicked off the song and solos were later sung by Fergie, Tim Gunn, Avril Lavingne, Josh Gad, Butler, Alannis Morissette, Leanne Rimes and Dave Grohl. Providing the signing for the number was Academy Award-winner Marlee Matlin.

“Goodbye to E! It’s time to move on. She wants to sing. She wants to dance and get her groove on,” went the chorus. Lavigne’s verse went, “She can’t go on faking every day that Chelsea cares about Kim and Kanye,” while Butler belted, “She’s off to Spain to find random guys to screw!”

Ellen DeGeneres Meets Chelsea Handler Nude In Shower

Aside from the celebrity chorus, one of the most notable moments of Handler’s farewell episode was a sketch with DeGeneres. In the pre-recorded bit, DeGeneres walks in on Handler taking a shower, determined to know why she’d never invited her onto her show. While Handler chalks it up to an oversight, DeGeneres claims it's because she’s a lesbian.

After claiming she didn't even know DeGeneres was a lesbian – and thought she was married to Ryan Seacrest – Handler decides to show DeGeneres she's completely comfortable being completely naked in the shower with the daytime talk show host by jumping around. Not impressed, DeGeneres tells Chuy he was her favorite part of the show before spinning on her heel out of the shower.

Handler, since deciding to leave E!, has signed a deal with Netflix that includes a stand-up special and an on-demand talk show.