Bonnie Franklin, best known for her role on the comedy One Day at a Time, passed away on Friday at her home in Los Angeles from complications from pancreatic cancer. She was 69.

Franklin played Ann Romano on One Day at a Time in the groundbreaking role of a divorced mother of two as she struggled to balance motherhood, her career and relationships. "Ms. Franklin helped define and illuminate the role of single-working mothers within the cultural landscape," CBS said in a statement. The show ran for a total of nine seasons.

After her run on One Day at a Time, Franklin guest starred on TV shows, including Hot in Cleveland and soap opera The Young and the Restless. She also spent time in the director’s chair of The Munsters Today – a show she appeared in during her early acting days. She also had parts on Gidget, The Man from U.N.C.L.E. and Broadway show Applause for which she earned a Tony nod before landing her role on One Day at a Time.

"Bonnie has always been one of the most important women in my life and was a second mother to me," said actress Valerie Bertinelli who played her daughter on the show. "She taught me how to navigate this business and life itself with grace and humor, and to always be true to yourself. I will miss her terribly."

Franklin’s husband of 29 years, producer Marvin Minoff, predeceased her in 2009. She is survived by her mother, Claire Franklin, and her stepchildren Jed and Julie Minoff.

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