Angie Harmon and her longtime husband, former NFL star Jason Sehorn, have decided to separate.

Angie Harmon, Jason Seahorn Split

Harmon's rep announced her reportedly amicable separation from Sehorn in a statement. “For the sake of their children, they ask for respect and privacy as they navigate this time in their lives," the rep told People magazine.

Harmon, 42, and Sehorn, 43, have opened up in the past about the difficulty of balancing work life and family life, especially since Harmon films Rizzoli & Isles in California, while the family is based in North Carolina. "We don't get out Friday nights early enough to catch a flight home," Harmon told Your Tango in 2011. "So I'm here [in L.A.]. We sometimes meet in Texas, a 2½-hour flight for both of us. I miss my kids, so it's hard, but my children are so understanding."

She added, "You have to be really considerate of each other, really kind to each other. It's a lot of work."

Check Out uInterview's Q&A With Angie Harmon HERE

Sehorn had proposed to Harmon on The Tonight Show with Jay Leno back in 2000. The couple married in June 2001, two years after they first started dating. Together, Harmon and Sehorn have three children – Finley, 11, Avery, 9 and Emery, 5.

Harmon is best known for playing Jane Rizzoli on Rizzoli and Isles and A.D. A. Abbie Carmichael on Law & Order. As for Sehorn, he played the majority of his professional football career at cornerback for the New York Giants. Now retired, Sehorn currently serves as the Director of Communications at Sonic Automotive and works as a college football analyst for ESPNU.

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