After 30-Pound Weight Loss, Amy Schumer Opens Up About Upsetting Side Effects Of Ozempic: ‘I Was Bedridden!’

Following her 30-pound weight loss due to Ozempic, iconic comedian Amy Schumer has revealed the gravity of the side effects the medication had on her. 

Ozempic, a medication intended to be used for type 2 diabetes, has become an increasingly popular weight loss drug, despite extensive evidence it causes a variety of health problems in those who don’t need it. A semaglutide, Ozempic effectively mimics hormones related to appetite to manufacture the feeling of being full.

On Jan. 29’s episode of The Howard Stern Show, Schumer explained, “I have this gene, GDF15, which makes you extremely prone to nausea.” She added that was, “Why I was so sick during my pregnancy.”

Schumer continued, “So, I tried Ozempic almost three years ago, and I was like, bedridden. I was like, vomiting — and then you have no energy. But other people take it, and they’re all good. God bless them.”

She remembered, “I tried it, and I was vomiting, and I’m in bed. My son’s like, ‘Can you play tag?’ I’m like, ‘I can’t.’ I was shriveling…I lost 30 pounds so quick. I looked great, but I couldn’t lift my head off the pillow, so what’s the point?”

In June 2023, Schumer called out other celebrities for lying about their use of Ozempic. On an episode of Watch What Happens Live, she declared, “Everyone’s like: ‘Smaller portions! Like shut the f— up. You are on Ozempic or one of those things or you got work done. Just stop…Be real with the people. When I got lipo, I said I got lipo.”

At the time, Schumer recounted to the host, “I was one of those people that felt so sick and couldn’t play with my son. I was so skinny, and he’s throwing a ball at me, and [I couldn’t].”

Oprah Winfrey, another celebrity vocal about the need for stars to be honest about when they have had work done, recently emphasized this point in an episode of her Super Soul podcast. The media mogul explained her preconceptions about weight. “One of the things that I realized the very first time I took a GLP-1 was that all these years, I thought that thin people had more willpower…They ate better foods. They were able to stick to it longer. They never had a potato chip.”

However, she revealed that she soon learned that willpower was not the issue but rather that people were medicating themselves to suppress their appetite.