BREAKING: Johnny Depp & Longtime Partner Vanessa Paradis Split After 14 Years

Things have officially run their course between Pirates of the Caribbean star Johnny Depp, 49, and his longtime lady, French actress Vanessa Paradis, 39, who have been together for 14 years and have two children, Lily-Rose, 13, and Jack, 9, together.

Depp and Paradis "have amicably separated," Depp's publicist said in a statement, reports Entertainment Tonight. "Please respect their privacy and, more importantly, the privacy of their children," the statement went on to read.

Depp and Paradis have dodged rumors about the state of their relationship for the past year after it was revealed that the two ultimately lived separate lives, according to People. "It's so sad," an insider said at the time about their non-relationship. Paradis and Depp haven't been seen on the red carpet together in over a year.

Paradis spoke recently about her and Depp's decision not to marry. "I love the romance of 'let's get married,'" she said. "But then, when you have it so perfect ... I mean, I'm more married than anybody can be — we have two kids. Maybe one day, but it's something I can really do without," she told Elle.

For more on Johnny Depp and Vanessa Paradis:

Johnny Depp, Justin Bieber Get Behind 'Bully' Campaign

WATCH: Johnny Depp In 'Dark Shadows' Trailer

Johnny Depp In New 'Rum Diary' Clips

Johnny Depp To Play Tonto In 'Lone Ranger' Remake

Vanessa Paradis Addresses Johnny Depp Breakup Rumors

VIDEO: Johnny Depp Surprises London School With Visit

Johnny Depp's Secret Island

Johnny Depp Discusses Marriage, Angelina Jolie

SPOILERS: Johnny Depp Pays Tribute With 'Rum Diary'

Johnny Depp Album Criticized By Christian Groups

Johnny Depp & Penelope Cruz Open 'Pirates Of The Caribbean' At Cannes